National Jewish Health

This small pilot study tested whether inhaling a drug called rh-DNase for 4 weeks could help people with neutrophilic asthma, a type that often doesn't respond well to standard treatments. Nineteen adults with confirmed asthma and signs of airway inflammation took part. The goal …

This study looked at sputum (mucus) from 83 adults with cystic fibrosis who were hospitalized for sudden lung worsening (called a pulmonary exacerbation). Researchers used genetic testing to find which antibiotic-resistant bacteria were present and compared those results to how w…

This study looked at 29 adults with cystic fibrosis who were hospitalized for a lung infection. Researchers collected blood, sputum, and urine to study how infection and inflammation affect recovery of lung function. The goal is to find better ways to personalize treatment and im…

This study followed 360 adults and children with chronic medical conditions to see how long their immune protection lasts after COVID-19 vaccination. Researchers measured antibody, T cell, and B cell responses before vaccination and every 3 months for 18 months. The goal is to un…

This study followed 58 adults with cystic fibrosis (CF) who were starting or switching to a new CFTR modulator medication as part of their regular care. Researchers collected blood, sputum, urine, and quality-of-life surveys before and after treatment to see how inflammation, lun…