Which asthma inhaler works better? study pits advair against symbicort

NCT ID NCT01117116

Completed Disease control Sponsor: National Jewish Health Source: ClinicalTrials.gov ↗

First seen Jul 06, 2026 · Last updated Jul 07, 2026 · Updated 1 time

Summary

This study compares two widely used asthma inhalers—Advair and Symbicort—to see if they have different effects on airway constriction. Researchers use a methacholine challenge test to measure how sensitive the airways are after four weeks of treatment. The study includes 20 adults with asthma who are already using a short-acting inhaler. Results may help guide which medication works best for individual patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: fluticasone propionate and salmeterol (Advair) vs budesonide and formoterol (Symbicort)
What this could lead to: If one drug proves more effective at preventing airway constriction, it could help doctors choose the better treatment for asthma control.
What could go wrong: This is a small, early-phase study with only 20 participants, so results may not apply to everyone with asthma. Individual responses vary.

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Conditions

The condition(s) this trial relates to.

asthma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ASTHMA

Contacts and locations

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Locations

National Jewish Health

Denver, Colorado, 80206, United States

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