National Institutes Of Health Clinical Center (cc)

This early-stage study tests a potential new dengue vaccine in 127 healthy adults aged 18 to 59. Researchers want to see if the vaccine is safe and how the immune system responds, especially in people who have been exposed to dengue before. Participants receive one shot and are c…

This study looks at whether a simple blood test called MCV can help doctors decide when to remove blood from people with hereditary hemochromatosis, a condition where the body absorbs too much iron. About 622 participants aged 15 and older will have regular blood draws to lower t…

This study looks at whether a newer antibiotic called cefiderocol works better than the best current treatments for a dangerous, drug-resistant bacterial infection (CRAB). Researchers will analyze data from about 5000 hospitalized adults to compare death rates within 28 days. The…

This study tests a laser device that destroys prostate cancer tumors using heat, guided by ultrasound instead of MRI. About 30 men with low- to intermediate-risk prostate cancer that hasn't spread will receive this focal treatment. The goal is to see if ultrasound guidance is pra…

This study looks at whether a 10-week exercise program can help adults who still have symptoms after a COVID-19 infection. Participants will do cardio exercise three times a week and attend weekly education classes. The goal is to see if exercise improves physical function and re…

This study tests a special needle with a tiny tracking device inside, like a mini GPS, to help doctors find hard-to-see tumors during biopsies or ablation procedures. About 3,900 adults with certain cancers or growths will take part. The goal is to see if this tool can place the …

This study looks at how healthy lungs respond to a substance that mimics a bacterial infection. Researchers will collect lung cells and fluid from 58 healthy, non-smoking adults to study inflammation and tiny molecules called microRNA. The goal is to better understand the body's …

This study aims to create computer programs that can help doctors detect and diagnose diseases from medical images like CT scans and MRIs. Researchers will use over 144,000 existing images from patients of all ages. The goal is to make image reading faster and more accurate, but …

This study looks at how assisted suicide is practiced in Switzerland by interviewing 25 Swiss experts, including doctors, academics, and right-to-die society representatives. The goal is to understand the policy, how it works in practice, and the ethical questions it raises. No t…

This study creates a registry to collect information about pregnancies and births among people who took part in NIH clinical trials. It includes up to 500 participants of any age who became pregnant while in a study or within one year after. Researchers will interview participant…

This study aimed to see if a virtual education program could help teenagers and young adults with congenital adrenal hyperplasia (CAH) learn to manage their own health care as they move from pediatric to adult doctors. It planned to enroll 16- to 22-year-olds already in a related…

This study watches how the trillions of bacteria living in and on our bodies change when someone stays in the hospital. Researchers will take daily swabs from the skin, throat, and rectal area, plus stool samples, from 250 patients aged 2 and older. The goal is to learn which ger…