Scientists spy on Lungs' first response to fake infection
NCT ID NCT02392442
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at how healthy lungs respond to a substance called endotoxin, which mimics a bacterial infection. Researchers will collect lung cells and fluid from 58 healthy, non-smoking adults using a thin tube inserted into the airways. The goal is to understand inflammation and the role of microRNA molecules in the lung's defense.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Endotoxin
What this could lead to
If successful, this could improve understanding of how the lungs fight infection and how microRNA influences inflammation.
What could go wrong
This is an early-stage study in healthy volunteers, not patients. It aims to understand basic biology, not test a treatment, so direct benefits are unlikely.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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National Institutes of Health Clinical Center
Bethesda, Maryland, 20892, United States