Scientists spy on Lungs' first response to fake infection
NCT ID NCT02392442
First seen Jun 26, 2026 · Last updated Jul 17, 2026 · Updated 3 times
Summary
This study looks at how healthy lungs respond to a substance called endotoxin, which mimics a bacterial infection. Researchers will collect lung cells and fluid from 58 healthy, non-smoking adults using a thin tube inserted into the airways. The goal is to understand inflammation and the role of microRNA molecules in the lung's defense.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Endotoxin
- What this could lead to
- If successful, this could improve understanding of how the lungs fight infection and how microRNA influences inflammation.
- What could go wrong
- This is an early-stage study in healthy volunteers, not patients. It aims to understand basic biology, not test a treatment, so direct benefits are unlikely.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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National Institutes of Health Clinical Center
Bethesda, Maryland, 20892, United States