National Institute On Drug Abuse (nida)
Clinical trials sponsored by National Institute On Drug Abuse (nida), explained in plain language.
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Brain scans and genes may hold key to quitting smoking
Knowledge-focused CompletedThis study looked at how nicotine addiction changes brain activity and which genes might make quitting harder. Researchers used brain scans and genetic tests on 159 people, including smokers trying to quit, smokers not trying to quit, former smokers, and non-smokers. The goal was…
Sponsor: National Institute on Drug Abuse (NIDA) • Aim: Knowledge-focused
Last updated May 17, 2026 02:43 UTC
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Gut bacteria linked to alcohol cravings in new study
Knowledge-focused CompletedThis study looked at how gut bacteria differ between people with alcohol use disorder who are currently drinking, those who are abstinent, and healthy moderate drinkers. Researchers collected stool samples and measured cravings in a bar-like setting. The goal was to understand if…
Sponsor: National Institute on Drug Abuse (NIDA) • Aim: Knowledge-focused
Last updated May 17, 2026 02:39 UTC
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Cocaine and experimental drug: a safety check
Knowledge-focused CompletedThis study looked at whether an experimental drug called SXC-2023 changes how the body reacts to cocaine. Nineteen adults who use cocaine but weren't seeking treatment took part. Researchers measured side effects and vital signs like heart rate and blood pressure after giving coc…
Phase: PHASE1 • Sponsor: National Institute on Drug Abuse (NIDA) • Aim: Knowledge-focused
Last updated May 14, 2026 12:04 UTC
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Brain scans reveal how drugs hijack your mind
Knowledge-focused CompletedThis study tested new computer tasks to see how drugs affect brain activity using MRI scans. Healthy volunteers aged 18 to 65, both drug users and non-users, performed memory and reaction-time tests while in a scanner. The goal was to develop reliable tools for future research on…
Sponsor: National Institute on Drug Abuse (NIDA) • Aim: Knowledge-focused
Last updated May 14, 2026 12:04 UTC
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Gadgets vs. addiction: can PDAs and GPS reveal hidden triggers?
Knowledge-focused CompletedThis study tested whether portable devices like PDAs and GPS units can give a more accurate, real-time picture of stress and drug use in people being treated for heroin addiction. About 373 participants carried these devices for 16 weeks while receiving methadone treatment. The g…
Sponsor: National Institute on Drug Abuse (NIDA) • Aim: Knowledge-focused
Last updated May 13, 2026 16:03 UTC
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Baltimore study reveals how your block shapes drug habits
Knowledge-focused CompletedThis study looked at how where you live in Baltimore might influence drug use, addiction, and whether people seek help. Over 1,600 adults from different neighborhoods gave blood, urine, and saliva samples, and answered questions about their health and habits. Researchers followed…
Sponsor: National Institute on Drug Abuse (NIDA) • Aim: Knowledge-focused
Last updated May 12, 2026 13:41 UTC
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Thousands screened for brain studies on addiction
Knowledge-focused CompletedThis study screened nearly 7,000 adults to find people who might be eligible for future research on drug addiction, treatments, and brain effects. Participants had phone and in-person interviews, medical exams, and lab tests. No treatment was given—this was only to build a pool o…
Sponsor: National Institute on Drug Abuse (NIDA) • Aim: Knowledge-focused
Last updated May 11, 2026 20:40 UTC
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Scientists search for genetic clues to addiction
Knowledge-focused CompletedThis study aimed to understand how genes might be linked to substance use disorders and related behaviors. Researchers collected genetic information and measured thinking skills, emotions, and decision-making in 847 adults, including healthy volunteers and people with substance u…
Sponsor: National Institute on Drug Abuse (NIDA) • Aim: Knowledge-focused
Last updated Apr 02, 2026 14:56 UTC