Gut bacteria may influence alcohol cravings, new study suggests

NCT ID NCT03152760

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study explores the link between gut bacteria and alcohol use disorder (AUD). Researchers compared gut microbiota in three groups: current heavy drinkers with AUD, people with AUD who have been abstinent for at least 4 weeks, and healthy moderate drinkers. Participants provided stool samples, underwent physical exams, and took part in cue-reactivity sessions in a bar-like setting to measure cravings. The goal is to understand if gut bacteria differ between these groups and if they relate to alcohol cravings.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could reveal how gut bacteria influence alcohol cravings, pointing toward new ways to treat alcohol use disorder.

What could go wrong

This is a small pilot study with only 35 participants, so results may not apply to everyone. It is designed to gather information, not to test a treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

alcohol abuse

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States