Massachusetts General Hospital

This study tested a combination treatment for people with advanced bladder cancer that has spread. It used a procedure called cryoablation (freezing tumors) along with immunotherapy drugs (pembrolizumab or avelumab) to see if the immune system could better attack remaining tumors…

This study tested a newer, more precise type of radiation called pencil beam proton therapy, given together with standard chemotherapy, for people with anal cancer. The goal was to see if this approach is practical and might cause fewer side effects than standard radiation. Twent…

This study tested whether adding the drug lenalidomide to a standard chemotherapy regimen (MEC) could help adults with acute myeloid leukemia (AML) that had come back or not responded to previous treatment. The trial enrolled 41 people aged 18 to 70. The main goal was to see how …

This study looked at whether tesamorelin, a drug that boosts growth hormone, can lower liver fat and improve liver health in 51 adults with nonalcoholic fatty liver disease (NAFLD) and obesity. Participants received either tesamorelin or a placebo for a period. The goal was to se…

This study tested a probiotic called INF108F in 20 breastfed infants with food protein-induced allergic proctocolitis (FPIAP), a condition causing blood in stool and digestive discomfort. The goal was to see if the probiotic could improve gut microbiome balance and reduce symptom…

This study tested a short, 3-session mind-body program called PACE CF for adults with cystic fibrosis who have ongoing pain. The program was delivered online by a member of their care team. Researchers wanted to see if the program was acceptable and helpful for managing pain and …

This study tested a new program called MASC (Mindful and Self-Compassionate Care Program) for caregivers of people with Alzheimer's or related dementias. The program teaches mindfulness, self-compassion, and behavior management skills to help reduce caregiver stress. 82 caregiver…

This study looked at whether analyzing social media messages (like WhatsApp and Instagram) can help identify young women at risk for HIV. Researchers collected 6 months of messages from 400 women aged 18-24 in Kisumu, Kenya, and used AI to detect patterns related to HIV risk. The…

This study tested a new program to help people with dementia and their caregivers who receive medical care at home. Researchers worked with two home-care practices to see if the program was practical and helpful. The goal was to improve quality of life and reduce caregiver stress…

This study compared two at-home colon cancer screening tests—FIT and Cologuard—in over 5,000 people aged 45-75 at community health centers. The goal was to see which test more people completed and which worked better in real-world settings. Participants received a test by mail an…