Mario Negri Institute For Pharmacological Research

This study tested whether adding ATRA (a vitamin A derivative) to the standard hormone therapy anastrozole could shrink tumors in postmenopausal women with a common type of early breast cancer (HR+/HER2-). The trial was planned for 76 participants but was terminated early, so res…

This study tested whether adding the immunotherapy drug durvalumab to standard chemotherapy could shrink large stage III lung cancers enough to allow safe radiation therapy. The trial included 10 patients whose tumors were too big for standard treatment. The goal was to see if mo…