Mario Negri Institute For Pharmacological Research

This study aims to confirm how well a two-drug maintenance treatment works to control advanced ovarian cancer after initial chemotherapy. It will involve about 190 women whose cancer has a specific genetic marker (HRD-positive) and who responded to first-line treatment. The goal …

This study compares two approaches to anti-rejection drugs after kidney transplant surgery. Researchers want to see if giving just one day of a powerful immune-suppressing drug works as well as giving it for seven days. They're looking at 75 kidney transplant patients to find out…

This study aims to create better tests to diagnose and monitor two rare, serious kidney diseases (aHUS and C3G). Researchers will analyze blood, cells, and tissue from about 180 patients and healthy people to find new markers of disease. The goal is to help doctors make faster, m…

This study aims to improve clinical trials for a rare genetic kidney disease called ADPKD by using artificial intelligence to create simulated patient data. Researchers will use real medical records from 100 patients to train AI models that generate artificial datasets that mimic…

This study aims to understand what patient characteristics can predict how quickly kidney function declines in people with a genetic kidney disease called ADPKD. Researchers will look back at the medical records of 70 patients who already received a specific long-term treatment c…

This study aims to find out which of two common blood tests is more accurate for measuring kidney function in people with nephrotic syndrome, a serious kidney condition. Researchers will compare the standard creatinine test with a newer test called cystatin C, using stored blood …

This project is creating a collection of medical images like MRIs and CT scans to help future research. It involves 300 adults, both healthy and those with kidney or brain conditions, who are donating their scans and related health information. The goal is to build a database tha…