Mario Negri Institute For Pharmacological Research

This study tested whether adding a diabetes drug (pioglitazone) to a standard chemotherapy (trabectedin) could better control advanced liposarcoma, a rare cancer of fat tissue. It involved patients whose cancer had stopped responding to the standard drug alone. The goal was to se…

This study tested a school-based program designed to prevent childhood obesity by promoting healthy eating and lifestyle habits. It involved 226 children aged 6-11 and their families in Italy. The goal was to see if educational activities in schools, combined with family involvem…

This was an observational study that aimed to understand if a specific genetic change (a deletion in the PKD2 gene) found in 10 patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD) came from a common ancestor in the Bergamo province of Italy. Researchers analyzed th…

This study aimed to understand why some patients with a kidney disease called membranous nephropathy do not get better with standard treatment. Researchers analyzed blood samples from 48 patients who had tried two newer therapies. They looked closely at specific immune cells to s…