Promising combo for breast cancer falls short: trial ends early

NCT ID NCT04113863

First seen Dec 26, 2025 · Last updated Apr 29, 2026 · Updated 19 times

Summary

This study tested whether adding ATRA (a vitamin A derivative) to the standard hormone therapy anastrozole could shrink tumors in postmenopausal women with a common type of early breast cancer (HR+/HER2-). The goal was to see if the combination worked better than anastrozole alone before surgery. However, the trial was stopped early, so the results are limited and no clear conclusions can be drawn.

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Contacts and locations

Locations

  • ASST Papa Giovanni XXIII

    Bergamo, 24127, Italy

  • Ospedale Santa Maria della Misericordia di Udine

    Udine, UD, 33100, Italy

Conditions

Explore the condition pages connected to this study.