Mind over tumor: short therapy may improve chemo response in breast cancer

NCT ID NCT07570368

Not yet recruiting Symptom relief Sponsor: Universitas Airlangga Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a short psychological therapy called Brief Acceptance and Commitment Therapy (Brief-ACT) can help chemotherapy work better in women with locally advanced breast cancer. Fifty-four participants will either receive standard chemotherapy alone or with Brief-ACT sessions. Researchers will measure tumor response, stress levels, and blood markers of inflammation and blood vessel growth.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Brief Acceptance and Commitment Therapy (Brief-ACT)
What this could lead to: If it works, this could show that adding a short psychological therapy to standard chemotherapy improves tumor response and reduces stress in breast cancer patients.
What could go wrong: This is a small, early-stage trial with only 54 participants, so results may not apply to all patients. The therapy may not significantly affect chemotherapy outcomes or biomarker levels.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm Stress, Psychological

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER BREAST NEOPLASM FEMALE LOCALLY ADVANCED BREAST CANCER LOCALLY ADVANCED BREAST CANCER (LABC)

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