Major Extremity Trauma Research Consortium

This study tests whether a substance called polyethylene glycol (PEG) can help reconnect damaged nerves in the arm more quickly and safely than standard surgery alone. About 40 adults with severe nerve injuries will be randomly assigned to receive either PEG plus surgery or surge…

This study tests whether taking antibiotics by mouth is as effective as receiving them through an IV for treating infected bone fractures that haven't healed properly. About 250 adults with this condition will be randomly assigned to 6 weeks of either oral or IV antibiotics, alon…

This study tests whether injecting a person's own skin cells into the residual limb can make the skin firmer and healthier for prosthetic use. Twenty adults with a below-knee amputation will receive either the cell injection or a placebo. The main goals are to check safety and se…