Could your own skin cells make a prosthetic limb fit better?
NCT ID NCT04839497
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase 2 trial is testing whether injecting a person's own skin cells into the residual limb can improve skin firmness for amputees who use a prosthetic. Twenty adults with a below-knee amputation will receive either the cell injection or a placebo. Researchers will monitor safety and measure changes in skin firmness over three months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- autologous volar fibroblast injection
- What this could lead to
- If it works, this could offer a way to improve skin firmness and comfort for amputees using prosthetics.
- What could go wrong
- This is a small early-phase trial with only 20 participants, so results may not apply to everyone. Possible side effects include bruising, swelling, or infection at the injection site.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Johns Hopkins Hospital
RECRUITINGBaltimore, Maryland, 21287, United States
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