Major Extremity Trauma Research Consortium
Clinical trials sponsored by Major Extremity Trauma Research Consortium, explained in plain language.
Upcoming readouts
Trials from this sponsor expected to report results within the next 12 months.
- Pill power: could oral antibiotics replace IV drips for infected fractures? Results expected Sep 2027 (estimated)
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New antibiotic cocktail aims to slash infection risk in severe bone breaks
Disease control Recruiting nowThis study tests whether a new antibiotic protocol can prevent infections in people with severe open fractures (where the bone breaks through the skin). The experimental group gets antibiotics applied directly to the wound before closure, plus extended systemic antibiotics. The c…
Phase 3 • Sponsor: Major Extremity Trauma Research Consortium • Aim: Disease control
Last updated Jul 24, 2026 00:00 UTC
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Pill power: could oral antibiotics replace IV drips for infected fractures?
Disease control Recruiting nowThis study compares oral (pill) antibiotics to intravenous (IV) antibiotics for treating infected broken bones that haven't healed properly. About 250 adults with this condition will be randomly assigned to receive either oral or IV antibiotics for up to 6 weeks after surgery. Th…
Phase 3 • Sponsor: Major Extremity Trauma Research Consortium • Aim: Disease control
Last updated Jun 27, 2026 13:08 UTC
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Can a vacuum dressing stop infections in high-risk leg fractures?
Disease control Recruiting nowThis study tests whether a negative pressure wound therapy (NPWT) device, placed over the surgical incision, can reduce infections and other wound complications compared to standard dressings in people with severe leg fractures. The trial will enroll 352 patients with high-risk t…
Phase 3 • Sponsor: Major Extremity Trauma Research Consortium • Aim: Disease control
Last updated Jun 27, 2026 12:31 UTC
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New gel fusion technique aims to speed nerve repair after traumatic arm injuries
Disease control Recruiting nowThis study tests whether a substance called polyethylene glycol (PEG) can help reconnect severed nerves in the arm more effectively than standard surgery. About 40 adults with a recent, complete nerve injury from trauma will receive either PEG plus standard repair or standard rep…
Phase 2 • Sponsor: Major Extremity Trauma Research Consortium • Aim: Disease control
Last updated Jun 27, 2026 09:09 UTC
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Could your own skin cells make a prosthetic limb fit better?
Symptom relief Recruiting nowThis phase 2 trial is testing whether injecting a person's own skin cells into the residual limb can improve skin firmness for amputees who use a prosthetic. Twenty adults with a below-knee amputation will receive either the cell injection or a placebo. Researchers will monitor s…
Phase 2 • Sponsor: Major Extremity Trauma Research Consortium • Aim: Symptom relief
Last updated Jun 27, 2026 07:54 UTC