Leo Pharma

This study looked at whether a higher dose of the drug brodalumab works better for people with moderate-to-severe plaque psoriasis who weigh over 120 kg. About 385 participants received either an adjusted higher dose or the standard dose for 52 weeks. The main goal was to see if …

This study tested a drug called tralokinumab for people with moderate-to-severe atopic hand eczema that hasn't improved with standard treatments. 235 adults received either the drug or a placebo every two weeks for 16 weeks, followed by everyone getting the drug for another 16 we…

This study tested a new psoriasis ointment (LEO 90100) against a standard one (Daivobet) in 604 Chinese adults with stable plaque psoriasis. Participants applied the treatment for 4 weeks, and doctors checked how much their skin cleared up. The goal was to see if the new ointment…

This study tested a cream called delgocitinib in 98 teenagers aged 12-17 with moderate to severe chronic hand eczema. Participants applied the cream twice daily for 16 weeks. The goal was to see if the cream could clear or nearly clear the eczema better than a cream with no activ…

This study tested a new ointment (LEO 124249) for people with chronic hand eczema that hasn't been well controlled with steroid creams. 91 participants applied the ointment twice daily for up to 8 weeks. The goal was to see if the ointment could clear or nearly clear the eczema c…

This study tested four different doses of an experimental drug called LEO 138559 (also known as Temtokibart) in 262 adults with moderate-to-severe atopic dermatitis (eczema). The goal was to see how well the drug reduces eczema severity and whether it is safe compared to a placeb…

This early-phase study tested a single injection of an experimental drug (LEO 158968) in 6 adults experiencing a gout flare. The main goal was to see if the drug could reduce joint pain to none or mild within a few days. Researchers measured pain using a simple 0-to-4 scale, aimi…

This study tested whether delgocitinib cream can cause a skin allergy when combined with UV light. Sixty healthy adults had the cream applied and then exposed to UV. Researchers checked for skin reactions to see if the cream is safe to use in sunlight.

This study tested two different ways of giving a single 300 mg dose of tralokinumab to 101 healthy adults aged 18 to 55. The goal was to see if one injection with a new device works as well as two injections with the current device. Researchers measured drug levels in the blood, …

This study tested whether delgocitinib, an experimental drug, changes heart rhythms in 40 healthy adults. Participants took the drug or a placebo, and their heart activity was measured with ECGs. The goal was to check for any risk of dangerous heartbeats, not to treat any disease…

This study looked at whether delgocitinib cream, a treatment for eczema, can make skin more sensitive to light. Thirty-five healthy adults had the cream applied to small areas of skin, then exposed to UV light. Researchers checked for redness, swelling, or blistering to see if th…

This early-stage study tested a new compound called LEO 158968 in 120 healthy adults aged 18 to 60. The main goal was to see what side effects it might cause and how well the body tolerates it. Researchers also measured how the drug moves through the body and whether it triggers …

This study looked at how much of the drug tacrolimus gets into the blood when applied as a cream to healthy skin. Twenty-four healthy adults applied the cream twice daily. Researchers measured drug levels and checked for side effects. The goal was to understand the drug's behavio…

This early-stage study tested the safety of a new drug called LEO 153339 in 108 healthy adults aged 18 to 65. Participants received either a single dose or multiple doses of the drug or a placebo. The goal was to see how the body handles the drug and whether it causes any side ef…