New shot aims to ease gout flare pain in early trial
NCT ID NCT06444867
First seen Oct 31, 2025 · Last updated Jun 23, 2026 · Updated 44 times
Summary
This early-phase trial tested a single injection of LEO 158968 in 6 people experiencing a gout flare. The main goal was to see if the drug could reduce joint pain to none or mild within a few days. Researchers also monitored safety and how the body processed the drug. Because it is a very small study, results are preliminary and not conclusive.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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LEO Pharma Investigational Site
Lille, 59400, France
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LEO Pharma Investigational Site
Venlo, 5912 BL, Netherlands
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LEO Pharma Investigational Site
London, EC2Y 8EA, United Kingdom
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
LEO 158968 (a drug given as a shot under the skin)
What this could lead to
If it works, this could point toward a new option for quickly reducing pain during a gout flare.
What could go wrong
This is a very early, tiny trial with only 6 people. It is not designed to prove effectiveness, and the drug may not work or could have side effects.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.