New ointment shows promise for stubborn hand eczema
NCT ID NCT02664805
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase 2a trial tested whether a new ointment called LEO 124249 can improve chronic hand eczema when applied twice daily for up to 8 weeks. 91 adults with hand eczema that didn't respond well to steroid creams took part. The study compared the active ointment to an inactive vehicle to see if it reduces redness, scaling, and itching.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- LEO 124249 ointment
- What this could lead to
- If it works, this could point toward a new topical treatment option for chronic hand eczema that is not adequately controlled by steroids.
- What could go wrong
- This is an early proof-of-concept trial with only 91 participants, so results may not apply to everyone. The ointment may not prove more effective than the vehicle (inactive base).
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Allergie-Centrum-Charité Klinik für Dermatologie, Venerologie und Allergologie
Berlin, 10117, Germany
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