King's College London

This study tests a new, less invasive cleaning method (MINST) for peri-implantitis, an infection that causes bone loss around dental implants. About 80 adults with the condition will receive either MINST or standard care. The goal is to see if MINST reduces deep pockets and bleed…

This study tests a therapy program called the Cannabis Clinic for Psychosis (CCP) to help people with first-episode psychosis reduce or stop using cannabis. About 80 adults who are dependent on cannabis and want to cut back will either receive the 12-session CCP therapy right awa…

This study is for people who have chest pain and shortness of breath but no blockages in their main heart arteries. The cause is often small vessel angina (CMD), which is hard to diagnose and treat. Researchers will test new ways to treat CMD by looking at how the heart uses ener…

This study tests whether a short virtual reality (VR) program is safe and acceptable for people receiving care for anorexia nervosa. 45 adults will use the VR app for about 20-30 minutes each weekday for one week, while continuing their usual treatment. The study focuses on wheth…

This study aims to understand how maternity clinicians (midwives and obstetricians) make decisions about medical interventions during childbirth. Researchers will observe and interview 200 clinicians to learn the reasons behind their choices. The goal is to gather insights that c…

This study aims to improve HIV outpatient care by routinely asking patients about their mental health, symptoms, and quality of life through a questionnaire called POSITIVE OUTCOMES. About 17,000 adults with HIV at five clinics in the UK and US will take part. Researchers will wo…

This study looks at how continuous positive airway pressure (CPAP) therapy affects the complexity of body signals like oxygen levels, heart rate, and breathing in adults with obstructive sleep apnea. Researchers will analyze data from 160 people who completed a previous trial, co…

This study aims to understand what 'complexity' means for children with life-limiting illnesses by talking to kids, parents, and professionals across health, education, and social care. The goal is to create a shared definition that helps coordinate better care and support. About…

This study looks at whether eating more fiber (40 grams per day) can improve gut health markers linked to early-onset colorectal cancer. About 200 adults in the UK will follow either the standard healthy eating guide or a higher-fiber version for 12 weeks. Researchers will measur…

This study tests a new, gentle device that collects tiny fluid samples from babies' skin without needles. Researchers will compare healthy babies and those with eczema to find chemical signals linked to the condition. The goal is to better understand what causes eczema in infants…

This study looks at whether cannabidiol (CBD) affects how much THC heavy cannabis users need to feel intoxicated. About 30 adults who use cannabis heavily will take a single dose of CBD or a placebo, then inhale THC from a vaporiser and decide when they've had enough. Researchers…

This research programme aims to understand how lifestyle, environment, genetics, and social factors influence healthy aging and overall wellbeing. It will recruit 100,000 people aged 12 and older across the UK, who can participate from home using digital tools and at-home sample …

This study looks at why some people improve more from anxiety treatment than others. Over 4,400 adults with high anxiety will use a digital brain training program called LENS, which helps change negative thinking patterns. Researchers will track changes in mood and thinking for f…