Jaeb Center For Health Research

This study tests whether people with wet age-related macular degeneration can use a home device to scan their own eyes daily, guiding when they need treatment. Currently, patients receive regular eye injections on a fixed schedule. The goal is to see if home monitoring can mainta…

This study looks at the best order to treat lazy eye (amblyopia) in children aged 3 to 12. Some kids get glasses and an eye patch at the same time, while others start with glasses alone and add patching later if needed. The goal is to see if both approaches improve vision equally…

This study tests whether an automated insulin pump (the iLet Bionic Pancreas) can help people aged 14 and older with cystic fibrosis-related diabetes keep their blood sugar in a healthy range. About 150 participants will either use the pump or their usual insulin method for 13 we…

This study looks at whether inhaled insulin (Afrezza) is safer than pump insulin for preventing low blood sugar during exercise after a meal in adults with type 1 diabetes. About 30 people aged 18-65 who use a Tandem insulin pump with Control-IQ will complete three exercise sessi…

This study tests whether special video treatments (dichoptic therapy) can improve vision in children aged 8 to 12 with amblyopia (lazy eye). About 252 kids will be randomly assigned to use Luminopia, Vivid Vision, or just wear glasses if needed. The main goal is to see if the tre…

This study tests two ways to treat proliferative diabetic retinopathy, a serious eye condition caused by diabetes. About 426 adults will get either eye injections of faricimab plus laser treatment, or surgery (vitrectomy) with laser. Researchers will track vision changes, number …

This study tests a new treatment for lazy eye (amblyopia) in children aged 4 to 7. Instead of wearing an eye patch for 2 hours daily, children watch specially designed movies or shows using a headset for 1 hour a day, 6 days a week. The goal is to see if this movie-watching metho…

This study tests whether using a continuous glucose monitor (CGM) early in pregnancy can quickly detect and manage high blood sugar in pregnant women. Researchers will track 6,000 women to see if this approach reduces problems for the baby (like being too large or needing intensi…

This study tests whether fenofibrate, a drug already used for high cholesterol, can stop diabetic retinopathy from worsening in people with mild to moderate eye damage. About 560 adults with diabetes will take either fenofibrate or a placebo for up to 6 years. If successful, this…

This study tests two different eye treatments to see if they can prevent vision loss in people who have had radiation therapy for a type of eye cancer called choroidal melanoma. The treatments are either an injection of faricimab or a tiny implant that slowly releases medicine. 6…

This study is for people with rare inherited retinal diseases that cause vision loss. It has two parts: a registry that collects genetic and eye health information, and a natural history study that tracks how vision changes over time. The goal is to better understand these rare c…

This study aims to find out how often people with cystic fibrosis-related diabetes (CFRD) develop complications like eye, kidney, and nerve problems. Researchers will also check blood pressure and cholesterol levels. About 200 adolescents and adults with CFRD for at least 5 years…

This study compares having surgery right away versus waiting until vision gets worse for people with a condition called epiretinal membrane (a thin layer of scar tissue on the eye's surface). Researchers want to see which approach leads to better vision over 3 years. About 400 ad…

This study observes children under 18 with uveitis, an eye inflammation condition. Researchers will collect information on the types of uveitis, patient characteristics, and past or current treatments. Participants attend one visit with their doctor; those newly diagnosed may als…