Jaeb Center For Health Research

This study tests whether tonabersat can reduce retinal swelling in people with diabetic macular edema who still have good vision. About 128 adults with type 1 or 2 diabetes will receive either tonabersat or a placebo. The main goal is to see if the drug decreases the thickness of…

This study tests whether lower doses of the drug bevacizumab can effectively treat a severe form of retinopathy of prematurity (ROP) in premature infants. The condition affects blood vessels in the eye and can lead to blindness. The trial enrolled 77 babies with type 1 ROP in zon…

This study follows 46 people with gyrate atrophy, a rare genetic condition that causes vision loss, over 4 years. Researchers measure ornithine levels in the blood and track changes in the retina using eye scans and photos. The goal is to learn how the disease progresses under st…

This study follows 103 adults with a genetic eye condition called retinitis pigmentosa caused by EYS mutations. Researchers will track changes in vision and eye structure over 4 years. The goal is to better understand how the disease progresses so that future clinical trials can …

This study looks at 300 adults with cystic fibrosis to understand how body composition, muscle strength, and nutrition relate to lung function. Researchers will compare simple tests like grip strength and walking distance with a standard body scan. The goal is to find better ways…

This study follows 127 people with a genetic eye condition called USH2A-related retinal degeneration, which can cause vision loss and hearing problems. Researchers measure changes in vision, retinal structure, and mobility over several years to better understand how the disease p…

This study follows 44 people with a rare genetic eye condition caused by PCDH15 mutations to see how their vision changes over 4 years. Researchers measure things like visual field, sharpness, and retinal structure. The goal is not to treat the disease but to learn how it progres…