New hope: eye injections may stop Radiation-Induced blindness

NCT ID NCT05844982

First seen Oct 31, 2025 · Last updated Apr 29, 2026 · Updated 27 times

Summary

This study tests two different eye treatments to see if they can prevent vision loss in people who have had radiation therapy for a type of eye cancer called choroidal melanoma. The treatments are either an injection of faricimab or a tiny implant that slowly releases medicine. 600 participants will be randomly assigned to receive one of these treatments or just be watched closely. The goal is to find out if these treatments can help keep vision sharp over the long term.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for VISUAL IMPAIRMENT are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Associated Retinal Consultants, P.C.

    RECRUITING

    Royal Oak, Michigan, 48073, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Byers Eye Institute at Stanford University

    RECRUITING

    Palo Alto, California, 94303, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Foundation for Vision Research and Retina Specialists of Michigan, P.C.

    RECRUITING

    Grand Rapids, Michigan, 49546, United States

    Contact Phone: •••-•••-••••

    Contact Email: •••••@•••••

  • IL Eye and Ear Infirmary-University of Illinois at Chicago

    RECRUITING

    Chicago, Illinois, 60612, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Mayo Clinic

    RECRUITING

    Rochester, Minnesota, 55905, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Midwest Eye Institute

    RECRUITING

    Indianapolis, Indiana, 46290, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Northwestern Memorial Group

    RECRUITING

    Chicago, Illinois, 60611, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Oregon Health & Science University

    RECRUITING

    Portland, Oregon, 97239, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Pittsburgh Clinical Trial Consortium

    RECRUITING

    Sewickley, Pennsylvania, 15143, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Retina Associates of Florida, LLC

    RECRUITING

    Tampa, Florida, 33609, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Retina Consultants

    RECRUITING

    Manchester, Connecticut, 06042, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Retina Consultants of Carolina, PA

    RECRUITING

    Greenville, South Carolina, 29605, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Retina Consultants of Texas, PA

    RECRUITING

    Bellaire, Texas, 77401, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Retina Research Institute, LLC

    RECRUITING

    St Louis, Missouri, 63128, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Retina-Vitreous Consultants, Inc.

    RECRUITING

    Monroeville, Pennsylvania, 15146, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tennessee Retina, PC

    RECRUITING

    Nashville, Tennessee, 37203, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Texas Retina Associates

    RECRUITING

    Lubbock, Texas, 79424, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Board of Regents of the University of Wisconsin System

    RECRUITING

    Madison, Wisconsin, 53705, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Cleveland Clinic Foundation DBA Cleveland Clinic Lerner College of Medicine

    RECRUITING

    Celveland, Ohio, 44120, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UT Southwestern Medical Center

    RECRUITING

    Dallas, Texas, 75390, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Iowa Department of Ophthalmology and Visual Sciences

    RECRUITING

    Iowa City, Iowa, 52242, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Wills Eye Hospital

    RECRUITING

    Philadelphia, Pennsylvania, 19107, United States

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.