Gruppo Italiano Malattie Ematologiche Dell'adulto

This trial is testing whether adding the drug daratumumab to standard chemotherapy can help more adults with very high-risk T-cell acute lymphoblastic leukemia (T-ALL) achieve deep remission. The study will enroll 31 adults aged 18-65 with specific high-risk features. Researchers…

This study is testing a personalized treatment plan for young adults with a hard-to-treat form of chronic lymphocytic leukemia (CLL). All participants start with a two-drug combination. Doctors then check for tiny amounts of leftover cancer cells and adjust the treatment plan. So…

This study is testing if adding a targeted drug called ponatinib to standard chemotherapy works better for adults with a specific, aggressive type of acute lymphoblastic leukemia (ALL). It aims to see if this combination can drive the cancer into deep remission, measured by a sen…

This study aims to understand how a protein called adrenomedullin helps leukemia cells survive and grow in the bone marrow. Researchers will collect blood and bone marrow samples from 72 adults newly diagnosed with acute myeloid leukemia (AML). They will study how this protein in…

This study aims to understand how specific blood cancers and their treatments affect patients' daily lives, symptoms, and overall well-being. Researchers are collecting quality-of-life surveys from 572 Italian patients recently diagnosed with these conditions. The goal is to gath…