Georgetown University

This study aimed to see if a medication called daratumumab could help improve nerve damage (peripheral neuropathy) in adults with a specific blood condition called MGUS. The trial planned to give participants injections of the drug over six months and measure changes in nerve fun…

This study is testing whether a 6-month home-based walking program can improve metabolic health markers like blood sugar and cholesterol in people with and without HIV. Participants will gradually increase their daily steps to about 10,000, tracked with an activity monitor. The g…

This study is testing whether telephone counseling from a trained peer coach can help young women with a strong family history of breast cancer. The program aims to reduce stress, help with decision-making about genetic testing, and provide emotional support. It compares this pee…

This study is testing whether adding a drug called cabozantinib to two existing immunotherapy drugs (nivolumab and ipilimumab) can better control advanced melanoma that cannot be removed by surgery. The main goal is to see if this combination helps patients live longer without th…

This study is testing whether adding a new drug called tiragolumab to two existing cancer drugs (atezolizumab and bevacizumab) can help control advanced non-squamous lung cancer that has worsened after prior treatment. It will enroll about 29 adults whose cancer has specific gene…

This study is testing whether a combination of three chemotherapy drugs can help control advanced bile duct or gallbladder cancer that has worsened after initial treatment. It will involve about 48 patients whose cancer progressed despite standard gemcitabine and platinum chemoth…

This study is testing whether combining two drugs, BXCL701 and pembrolizumab, can help control metastatic pancreatic cancer that has worsened after initial treatment. It will measure if patients' cancer stays stable or shrinks for at least 18 weeks. The trial is for adults with a…

This study is testing a combination of two drugs, venetoclax and rituximab, for adults with chronic lymphocytic leukemia (CLL) that has returned or stopped responding to other treatments. The goal is to see how well and how safely this drug pair can control the cancer. Researcher…

This study is testing whether a 6-month video game training program can help girls with Rett syndrome improve their ability to use their arms purposefully. The program aims to reduce repetitive hand movements that interfere with daily activities. Participants play specially desig…

This study is testing a new, easier way to help family members of people with a BRCA gene mutation learn about genetic testing. It compares a web-based education program followed by a short phone call to the usual way information is shared. The goal is to see if this approach hel…