New drug combo shows promise in advanced breast cancer trial

NCT ID NCT03964532

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-phase trial tests a two-step treatment for advanced breast cancer that cannot be cured with surgery or radiation. First, patients receive a drug called talazoparib alone, then both talazoparib and avelumab together. The main goal is to check safety and side effects, while also exploring how the drugs affect the immune system. About 24 adults with measurable tumors are participating.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ€” we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer breast carcinoma breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • MedStar Georgetown University Hospital

    Washington D.C., District of Columbia, 20007, United States

  • University of Utah, Huntsman Cancer Institute

    Salt Lake City, Utah, 84112, United States