New drug combo shows promise in advanced breast cancer trial

NCT ID NCT03964532

First seen Apr 20, 2026 · Last updated May 15, 2026 · Updated 5 times

Summary

This early-stage trial tests a two-step treatment for people with advanced breast cancer that cannot be cured by surgery or radiation. First, participants receive a drug called talazoparib alone, then both talazoparib and avelumab together. The main goal is to check safety and side effects, while also looking at how the drugs affect the immune system. About 24 adults with measurable tumors are taking part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • MedStar Georgetown University Hospital

    Washington D.C., District of Columbia, 20007, United States

  • University of Utah, Huntsman Cancer Institute

    Salt Lake City, Utah, 84112, United States

Conditions

Explore the condition pages connected to this study.