Georgetown University

This study is testing whether adding two immunotherapy drugs (durvalumab and tremelimumab) to standard chemotherapy is safe and effective for treating advanced non-small cell lung cancer in people who also have HIV. It will enroll 18 adults with stage IV lung cancer who are on st…

This study is testing whether combining two existing drugs, pembrolizumab and lenvatinib, can help control advanced cervical cancer that has worsened after standard treatment. It will involve about 35 women to see if the combination shrinks tumors and for how long. The goal is to…

This study is testing whether a drug called CPX-351 can help keep acute myeloid leukemia (AML) in remission for patients who have already achieved remission but are not eligible for a bone marrow transplant. The goal is to see if giving this drug as ongoing 'maintenance' therapy …

This study is testing which of two proven smoking cessation programs works better for people getting lung cancer screening. It will enroll 1,188 current smokers to compare phone counseling through a state quitline versus a health system's own program. The goal is to find the most…

This early-stage study is testing if a drug called azeliragon can protect women's hearts and thinking skills during chemotherapy for early breast cancer. Researchers want to see if adding azeliragon to standard chemo is safe and can reduce heart damage and 'chemo brain.' The tria…

This early-stage study is testing the safety and finding the right dose of a new drug combination (NEROFE plus doxorubicin) for people with advanced solid tumors that have specific genetic markers (KRAS mutation and ST2-positive). It will enroll 24 participants who have run out o…

This study is testing whether a drug called sacituzumab govitecan can help control advanced thymoma or thymic cancer that has worsened despite previous treatment. It will involve 18 adults who receive the drug through an IV every three weeks. Researchers will check if tumors shri…

This study is testing a gentler radiation treatment for people with HPV-positive throat cancer who have already had surgery. Researchers want to see if using a lower radiation dose and targeting only the neck (instead of the original tumor site too) works as well as the standard,…

This study is testing whether a 6-month telehealth program using smartphones can help cancer survivors prevent painful mouth sores and gum disease, improve their quality of life, and reduce body-wide inflammation. It will compare this program to usual care in 100 cancer survivors…

This study is testing a specific treatment plan for people with a hard-to-treat form of advanced lung cancer that has spread to distant lymph nodes. The goal is to see if giving a combination of chemotherapy and immunotherapy drugs *before* surgery can shrink the cancer enough to…

This study is testing a package of support strategies to help people at high risk for HIV in Malawi continue taking their prevention medications. It will compare standard care to enhanced support at clinics and community centers, focusing on helping people stick with both daily p…

This study is testing whether an online program can help Black men who have survived prostate cancer and are struggling with insomnia. It will compare a structured internet therapy program to a simple educational website. The main goal is to see if the online approach is practica…

This study is testing whether a special website can help adults who have had thyroid cancer feel better after radioactive iodine treatment. Researchers want to see if the website is easy to use and if it improves patients' overall well-being compared to just getting standard info…

This study is testing a new decision support tool designed to help high-risk Black and Latina women make informed choices about whether to add a breast MRI to their annual mammogram for cancer screening. Researchers will compare the tool against standard care to see if it improve…

This study is testing whether a special website helps people recently diagnosed with a moderate-risk thyroid cancer make a more informed decision about radioactive iodine treatment. About 408 participants will be randomly assigned to either use this interactive decision aid websi…