Georgetown University

This study tested a combination of two drugs, LEE011 and everolimus, in 12 people with advanced pancreatic cancer that had stopped responding to standard chemotherapy. The goal was to find the best dose and see if the combo could slow cancer growth. The approach aims to control t…

This study tested the safety and effects of nilotinib, a cancer drug, in 43 people with Dementia with Lewy Bodies (DLB). DLB is a common type of dementia that shares features with Parkinson's and Alzheimer's. The goal was to see if nilotinib is safe and changes brain biomarkers, …

This study tested whether a low dose of nilotinib, a drug already used for leukemia, is safe for people with Parkinson's disease. Researchers gave the drug or a placebo to 75 participants to check for side effects and measure changes in brain chemicals linked to Parkinson's. The …

This study tested a new combination of drugs (ABT-888 plus chemotherapy) in 64 people with pancreatic cancer that had spread. The goal was to see if adding ABT-888, which blocks cancer cells from fixing DNA damage, could make chemotherapy work better and shrink tumors. The study …

This study tested a low dose of nilotinib, a drug used for leukemia, in 37 people with mild to moderate Alzheimer's. The main goal was to check safety and see if the drug reaches the brain and affects Alzheimer's-related proteins. Researchers also looked at brain scans for amyloi…

This study tested a new software platform called OR PathTrac that helps track and reduce the spread of harmful bacteria during surgery. Researchers monitored 804 adult patients to see if the tool could lower infection risks. The goal was to improve infection control practices in …

This study looked at whether a few phone calls with a trained peer coach could help young women (ages 21-30) who have a family history of BRCA gene mutations. The goal was to see if this support lowers cancer-related distress and helps them make informed choices about genetic cou…