Cancer drug repurposed for Alzheimer's shows early promise in small trial

NCT ID NCT02947893

First seen Feb 14, 2026 · Last updated May 16, 2026 · Updated 11 times

Summary

This study tested a low dose of nilotinib, a drug normally used for leukemia, in 37 people with mild-to-moderate Alzheimer's. The goal was to see if the drug is safe and whether it can reach the brain and affect proteins linked to Alzheimer's. Participants took the drug or a placebo daily for 6 months, and researchers monitored side effects and measured changes in spinal fluid and brain scans.

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Contacts and locations

Locations

  • Georgetown University Medical Center

    Washington D.C., District of Columbia, 20057, United States

Conditions

Explore the condition pages connected to this study.