Eli Lilly And Company

This study tests a new once-daily oral pill called orforglipron against a weekly injection (dulaglutide) in 170 teens aged 10-18 with type 2 diabetes. The goal is to see if the pill works better at controlling blood sugar and is safe. Participants will be followed for about 61 we…

This early-stage trial tests a new drug called LY4152199 in about 215 adults with certain types of blood cancer (like follicular lymphoma or diffuse large B-cell lymphoma) that have already been treated. The drug is designed to help the body's immune cells attack the cancer. The …

This study tests a once-daily pill called orforglipron in adults with type 2 diabetes who plan to fast during Ramadan. The goal is to see if the drug helps control blood sugar and weight without causing harm. About 130 participants will take the pill for up to 48 weeks, with clin…

This early-stage study tests whether a new drug, eloralintide, can improve how the body responds to insulin and manage weight in 115 adults with overweight or obesity. Participants will receive either the drug or a placebo injection and be monitored for about 35 weeks. The goal i…

This early-stage study tests an experimental drug called LY4174794 in 108 healthy volunteers who are overweight or have obesity. The main goal is to check the drug's safety and how the body processes it, not to measure weight loss. Participants will receive either the drug or a p…

This early-stage trial will test a single dose of a new drug called LY3971297 in 90 people with two types of heart failure: preserved ejection fraction (HFpEF) and reduced ejection fraction (HFrEF). The main goal is to see if the drug is safe and what side effects occur. Particip…

This study will test a wearable headband called Somfit that measures brain activity during sleep in people with early or no Alzheimer's symptoms. Researchers want to see if it works as well as a full lab sleep test. If it does, it could make it easier to track sleep changes linke…

This study tests a new, non-invasive eye scan that uses artificial intelligence to look for changes linked to Alzheimer's disease. Researchers will compare the scan results with blood tests in 200 UAE adults who have mild memory problems. The goal is to see if this quick, painles…

This Phase 2 trial tests an oral drug called LY4065967 in 150 people with chronic low back pain lasting at least 3 months. Half will get the drug, half a placebo, to see if it safely reduces pain and improves daily function. The study is not yet recruiting.

This Phase 2 trial tests an experimental oral drug, LY4065967, for knee pain caused by osteoarthritis. About 150 adults with chronic knee pain and confirmed osteoarthritis will receive either the drug or a placebo. The main goal is to see if the drug safely reduces pain intensity…

This study looks at how eating a high-fat or low-fat meal changes the way the body absorbs the drug tersolisib. Healthy volunteers receive two doses of tersolisib—one on an empty stomach and one with a meal—and have blood tests to measure drug levels. The goal is to understand wh…

This study will measure how much of the drug mirikizumab passes into breast milk in 14 breastfeeding women who take it for inflammatory bowel disease. Participants will provide milk samples over several weeks. The goal is to understand potential exposure to nursing infants, helpi…