Eli Lilly And Company

This early-stage trial is testing whether a new drug called macupatide, given alone or with another drug called eloralintide, is safe and well-tolerated in Japanese adults with obesity or overweight who do not have type 2 diabetes. Participants will receive multiple doses and sta…

This trial is testing an investigational drug called brenipatide in adults with moderate-to-severe COPD. Participants will receive either brenipatide or a placebo for about a year, alongside standard care. The goal is to see if brenipatide improves lung function and reduces the n…

This early-stage trial will test a single dose of a new drug called LY3971297 in 90 people with two types of heart failure: preserved ejection fraction (HFpEF) and reduced ejection fraction (HFrEF). The main goal is to see if the drug is safe and what side effects occur. Particip…

This early-stage trial is testing whether an investigational drug called eloralintide can slow down how quickly the stomach empties, which may help people feel fuller longer and support weight management. The study involves about 56 adults who are overweight or have obesity but a…

This study tests a new once-daily oral pill called orforglipron against a weekly injection (dulaglutide) in 170 teens aged 10-18 with type 2 diabetes. The goal is to see if the pill works better at controlling blood sugar and is safe. Participants will be followed for about 61 we…

This study tests a once-daily pill called orforglipron in adults with type 2 diabetes who plan to fast during Ramadan. The goal is to see if the drug helps control blood sugar and weight without causing harm. About 130 participants will take the pill for up to 48 weeks, with clin…

This study will test a wearable headband called Somfit that measures brain activity during sleep in people with early or no Alzheimer's symptoms. Researchers want to see if it works as well as a full lab sleep test. If it does, it could make it easier to track sleep changes linke…

This study tests a new, non-invasive eye scan that uses artificial intelligence to look for changes linked to Alzheimer's disease. Researchers will compare the scan results with blood tests in 200 UAE adults who have mild memory problems. The goal is to see if this quick, painles…

This Phase 2 trial tests an oral drug called LY4065967 in 150 people with chronic low back pain lasting at least 3 months. Half will get the drug, half a placebo, to see if it safely reduces pain and improves daily function. The study is not yet recruiting.

This Phase 2 trial tests an experimental oral drug, LY4065967, for knee pain caused by osteoarthritis. About 150 adults with chronic knee pain and confirmed osteoarthritis will receive either the drug or a placebo. The main goal is to see if the drug safely reduces pain intensity…

This early-stage trial is testing an investigational drug called LY4355756 in healthy volunteers to see how safe it is and how the body absorbs it. Participants will receive the drug as an oral capsule or tablet, with some also receiving midazolam to check for drug interactions. …

This early-phase study tests an experimental oral drug called LY4268989 (MORF-057) in 50 healthy adults. Researchers want to see if two different tablet forms are processed similarly by the body, and how meals affect that process. Participants will stay at a research unit for 18 …

This early-stage trial studies how healthy adults process two different liquid versions of the experimental drug eloralintide. The goal is to compare their safety and how the body absorbs and clears each version. Participants receive a single injection and are monitored for about…

This early-stage trial evaluates the safety and tolerability of a new drug called LY4178256 in healthy volunteers. Participants receive either the drug or a placebo intravenously, and researchers monitor side effects and how the body processes the drug. The study lasts about 7 mo…

This study will measure how much of the drug mirikizumab passes into breast milk in 14 breastfeeding women who take it for inflammatory bowel disease. Participants will provide milk samples over several weeks. The goal is to understand potential exposure to nursing infants, helpi…