Duke University

This study looks at whether giving a lower dose of radiation (20 Gy instead of 30 Gy) to a smaller area can still keep lymphoma from coming back after chemotherapy. It involves 241 adults with diffuse large B-cell lymphoma whose PET scans were clear after treatment. The goal is t…

This study tests whether a non-invasive brain stimulation technique called TMS can help heavy cannabis users reduce their use. Fifty near-daily users will receive either real or fake (placebo) TMS over five days. Researchers will measure changes in cannabis use and brain activity…

This study tests a structured nutrition plan for 300 ICU patients who had abdominal surgery and cannot eat normally. The plan uses tube feeding, oral supplements, and a device to measure calorie needs. Researchers will track infections, hospital stay length, and muscle changes to…

This study tests whether a rapid form of brain stimulation (accelerated TMS) can improve hand function in people with focal hand dystonia, a condition that causes muscle cramps during tasks like writing. Twenty-one adults will receive four TMS sessions in one day, and researchers…

This study tests whether a noninvasive brain stimulation technique called TMS, guided by fMRI brain scans, can improve neck muscle control in people with cervical dystonia. Fifty adults with the condition will receive four TMS sessions in one day, and researchers will measure cha…

This study was designed to learn how body weight changes the way etanercept works in people with rheumatoid arthritis or juvenile idiopathic arthritis who are also obese. Researchers planned to measure drug levels and disease activity in both adults and children starting the medi…

This study follows about 468 people with advanced kidney cancer to see how their treatment and quality of life change over time in real-world settings. Researchers will collect information from patients, doctors, and medical records to understand what treatments are used and how …

This study looks at whether stroke patients who do high-intensity rehabilitation at home recover their physical function as well as those who go to an inpatient rehab facility. Researchers will observe 500 patients who choose home rehab and compare their outcomes to similar patie…

This study tests a method to help prevent decompression sickness (the bends) in astronauts during spacewalks. Healthy volunteers aged 18-50 will breathe pure oxygen for 6 hours, then spend 6 hours in a low-pressure chamber while doing exercises. Researchers will monitor for bubbl…

This study tests a new, low-cost eye scanner to see if it can take clear pictures of the retina, the back of the eye. Researchers will compare it to a standard, expensive scanner. They will also use the device to measure retinal changes in people with mild Alzheimer's, aiming to …