Duke University
Clinical trials sponsored by Duke University, explained in plain language.
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Can smartphones and nurses tame diabetes and hypertension?
Disease control CompletedThis study looked at whether using mobile monitoring devices along with nurse support can help people better manage type 2 diabetes and high blood pressure. 220 adults with poorly controlled diabetes and high blood pressure took part. Researchers measured changes in blood sugar a…
Phase: NA • Sponsor: Duke University • Aim: Disease control
Last updated Apr 29, 2026 00:21 UTC
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One shot before surgery may be enough to prevent infection
Disease control CompletedThis study looked at the best timing for antibiotics in adults having knee replacement surgery. About 1,770 people took part. The goal was to see if a single dose before surgery works as well as a full day of antibiotics to prevent joint infections.
Phase: PHASE4 • Sponsor: Duke University • Aim: Disease control
Last updated Apr 29, 2026 00:21 UTC
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Pregnant women: is it safe to get COVID and flu shots at once?
Prevention CompletedThis study looked at whether it's safe for pregnant women to receive the COVID-19 and flu vaccines at the same time or a week or two apart. About 100 pregnant women took part, and researchers tracked side effects and pregnancy outcomes like preterm birth. The goal was to find the…
Phase: PHASE4 • Sponsor: Duke University • Aim: Prevention
Last updated Apr 29, 2026 00:21 UTC
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New study targets exercise struggles in long COVID patients
Symptom relief CompletedThis study tested different treatments to help people with Long COVID who have trouble exercising or feel very tired after activity. It involved 660 adults who had a past COVID-19 infection. The goal was to find ways to improve their ability to be active and their overall quality…
Phase: NA • Sponsor: Duke University • Aim: Symptom relief
Last updated Apr 29, 2026 00:21 UTC
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New hope for picky eaters: study tests treatments for kids with ARFID
Symptom relief CompletedThis study tested two different programs to help children aged 5 to 9 with Avoidant/Restrictive Food Intake Disorder (ARFID), a condition where kids can't eat enough or a wide enough variety of food. The goal was to see if these programs could reduce severe symptoms and improve n…
Phase: NA • Sponsor: Duke University • Aim: Symptom relief
Last updated Apr 29, 2026 00:21 UTC
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New study targets sleep troubles in long COVID patients
Symptom relief CompletedThis study tested different treatments to help people with Long COVID who have sleep problems like feeling very sleepy during the day or trouble sleeping at night. About 830 adults took part. The goal was to see if treatments matched to specific sleep issues could improve symptom…
Phase: PHASE2 • Sponsor: Duke University • Aim: Symptom relief
Last updated Apr 29, 2026 00:21 UTC
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New pain block may reduce opioid use after gynecologic surgery
Symptom relief CompletedThis study tested a nerve block (rectus sheath block) using a long-acting numbing medicine to control pain after gynecologic cancer surgery. Thirty patients received the block and were compared to 60 similar patients who had standard pain treatment. The goal was to see if the blo…
Phase: PHASE4 • Sponsor: Duke University • Aim: Symptom relief
Last updated Apr 28, 2026 13:02 UTC
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New telehealth approach aims to ease ADHD symptoms in preschoolers
Symptom relief CompletedThis study tested two telehealth programs for preschoolers with ADHD. Caregivers, doctors, and health experts gave feedback to improve the programs. The goal was to help children sleep better and reduce attention problems. The study included 46 children ages 3 to 5.
Phase: NA • Sponsor: Duke University • Aim: Symptom relief
Last updated Apr 28, 2026 13:02 UTC
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Scientists hunt for missing genetic clues in mysterious diseases
Knowledge-focused CompletedThis study looked for new genetic changes that might cause inherited diseases, especially in people who already have a diagnosis but unclear genetic test results. Researchers studied 56 patients and their family members to find hidden DNA variants. The goal was to better understa…
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Apr 29, 2026 00:22 UTC
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New program aims to help african american parents thrive
Knowledge-focused CompletedThis study tested a program to help African American families expecting a baby in late 2024. The goal was to see if the program was practical and well-liked by parents. 44 families from North Carolina took part in group sessions online. Researchers measured how acceptable and hel…
Phase: NA • Sponsor: Duke University • Aim: Knowledge-focused
Last updated Apr 29, 2026 00:22 UTC
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Video education boosts hospital bathing compliance
Knowledge-focused CompletedThis study tested whether showing hospitalized patients a short educational video improves their use of special antibacterial (CHG) wipes, which help prevent serious bloodstream infections from central lines. About 1000 adults took part. The goal was to see if the video helps mor…
Phase: NA • Sponsor: Duke University • Aim: Knowledge-focused
Last updated Apr 29, 2026 00:21 UTC
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Heart test upgrade may spot hidden stiffness in breathless patients
Knowledge-focused CompletedThis study looked at whether taking additional images during a standard exercise stress echocardiogram can help doctors figure out if chest pain or shortness of breath is caused by a stiff heart condition called HFpEF. Researchers enrolled 30 adults aged 50 and older who were alr…
Phase: NA • Sponsor: Duke University • Aim: Knowledge-focused
Last updated Apr 29, 2026 00:21 UTC
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New approach boosts cancer screening for women with HIV
Knowledge-focused CompletedThis study tested a new way to help women living with HIV get screened for HPV, a virus that can cause cervical cancer. The approach used simple messages and videos to address fears and misunderstandings. About 982 women in Kenya took part, and the goal was to see if more women w…
Phase: NA • Sponsor: Duke University • Aim: Knowledge-focused
Last updated Apr 29, 2026 00:20 UTC
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Can trusted voices and videos increase COVID testing?
Knowledge-focused CompletedThis study aimed to understand what helps or hinders COVID-19 testing among Black/African American adults. Researchers tested whether culturally relevant videos and trusted community leaders could encourage more people to get tested. Over 300 participants from beauty salons and b…
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Apr 28, 2026 13:02 UTC
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Wearable sensors show promise for detecting knee changes
Knowledge-focused CompletedThis study tested whether a wearable sensor could detect changes in how the knee moves and bears weight after a temporary injection of fluid into the knee joint. Fourteen healthy adults participated, and researchers measured their walking patterns before and after the injection. …
Phase: NA • Sponsor: Duke University • Aim: Knowledge-focused
Last updated Apr 28, 2026 13:02 UTC
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Heart risks may worsen brain decline in hispanic Parkinson's patients
Knowledge-focused CompletedThis study explored why Hispanics with Parkinson's disease often have more thinking and memory problems. Researchers looked at heart-related risks like diabetes, high blood pressure, and obesity in 40 participants from California and North Carolina. The goal was to understand how…
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Apr 28, 2026 13:02 UTC