Duke University

This study tests whether long-acting HIV prevention shots and opioid use disorder medications work well for people in prison who are close to release. About 300 adults will receive these treatments and be followed to see how well they stick with them and whether they reduce HIV r…

This study tests if a special nerve block (ESP block) can better control pain and reduce the need for strong painkillers after spinal fusion surgery. About 75 adults having back or neck fusion will receive either a standard painkiller or the nerve block. Researchers will measure …

This study compares two FDA-approved eye drops, Upneeq and Lumify, to see which one lifts droopy eyelids better in adults with acquired ptosis. About 50 participants will receive each drop at separate visits, and eyelid height will be measured an hour later. The goal is to find a…

This study tests two different methods of numbing the front-inside of the knee in healthy volunteers. One method targets the saphenous nerve, while the other also targets an additional nerve to the knee muscle. The goal is to see which approach provides better numbness without we…

This study looks at how a targeted nerve block near the wrist affects blood flow in healthy volunteers. Twenty people will have their hand blood flow and temperature measured before and after the block, using sensors and thermal cameras. The goal is to understand the body's autom…

This study tests a short video where Black women share their labor pain experiences. Doctors who watch it may become more empathetic, which could help build trust with their Black patients. About 120 people, including doctors and new mothers, will take part. The goal is to improv…