Duke University
Clinical trials sponsored by Duke University, explained in plain language.
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New CT scanner may spot more spinal fluid leaks in headache patients
Diagnosis Not yet recruitingThis study compares two types of CT scans used to find abnormal connections between spinal fluid and veins in people with spontaneous intracranial hypotension (low pressure headaches). Researchers will enroll 200 adults with confirmed diagnosis and brain MRI signs. The goal is to…
Phase: NA • Sponsor: Duke University • Aim: Diagnosis
Last updated Jun 12, 2026 12:06 UTC
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New app aims to tame anger in veterans with brain injury and PTSD
Symptom relief Not yet recruitingThis study will test a mobile app called CALM designed to help veterans with traumatic brain injury (TBI) and post-traumatic stress disorder (PTSD) control anger and impulsivity. About 100 veterans and a family member or friend will be split into two groups: one using the CALM ap…
Phase: NA • Sponsor: Duke University • Aim: Symptom relief
Last updated Jun 12, 2026 12:09 UTC
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Vitamin B6 may tame mood swings from brain tumor seizure drug
Symptom relief Not yet recruitingThis study looks at whether taking vitamin B6 can reduce mood-related side effects (like anger) caused by the seizure medicine levetiracetam in people with brain tumors. About 50 adults with brain tumor-related epilepsy who have been on levetiracetam for 6 weeks to 6 months will …
Phase: NA • Sponsor: Duke University • Aim: Symptom relief
Last updated Jun 12, 2026 12:04 UTC
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New ultrasound tech aims to see through bone and air
Knowledge-focused Not yet recruitingThis study will test a new ultrasound device that creates 4D moving images of the upper airway. Current ultrasound cannot see past bone or air-filled spaces, but this device aims to overcome that. About 100 healthy adults will lie still while the device scans their neck and jaw a…
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 12, 2026 12:03 UTC