Duke University
Clinical trials sponsored by Duke University, explained in plain language.
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Knee surgery infection study: one antibiotic dose may be enough
Disease control CompletedThis study looked at how to best use antibiotics to prevent infections in people having knee replacement surgery. About 1,770 adults were split into groups that got antibiotics either just before surgery or for a full day after. The goal was to see if a single dose works as well …
Phase: PHASE4 • Sponsor: Duke University • Aim: Disease control
Last updated Jun 12, 2026 12:07 UTC
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HIIT and weights show promise for stem cell recovery
Symptom relief CompletedThis study looked at whether 12 weeks of high-intensity interval training (HIIT) and resistance training could help people who had a stem cell transplant for blood cancer. It involved 16 patients and their caregivers. The goal was to see if exercise improves physical function, th…
Phase: NA • Sponsor: Duke University • Aim: Symptom relief
Last updated Jun 12, 2026 12:07 UTC
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New approach cuts opioid use after surgery, study finds
Symptom relief CompletedThis study tested ways to better manage pain after outpatient surgery, aiming to reduce the need for opioid painkillers and their side effects. Over 900 adults having same-day or short-stay surgery took part. The goal was to improve pain treatment while lowering the risk of opioi…
Phase: PHASE4 • Sponsor: Duke University • Aim: Symptom relief
Last updated Jun 12, 2026 12:06 UTC
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Can we fix long COVID fatigue? major trial tests exercise-boosting treatments
Symptom relief CompletedThis study tested different treatments to help people with Long COVID who struggle with exercise and feel very tired after activity. 660 adults took part across multiple medical centers. The goal was to find ways to improve daily activity and quality of life.
Phase: NA • Sponsor: Duke University • Aim: Symptom relief
Last updated Jun 12, 2026 12:06 UTC
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Your own note could spark better health talks
Knowledge-focused CompletedThis study tested whether having patients write a short note about their personal goals before a checkup would lead to more conversations about their future care. Twenty adults with a chronic illness took part. The main goal was to see if these conversations were recorded in thei…
Phase: NA • Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 12, 2026 12:07 UTC
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Hair salons and barbershops join fight to increase COVID testing
Knowledge-focused CompletedThis study looked at what helps or hinders COVID-19 testing among Black/African American adults. Researchers worked with beauty salons and barber shops to share culturally relevant videos and messages from trusted community leaders. The goal was to understand attitudes and increa…
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 12, 2026 12:03 UTC
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Can better sleep lower heart risks for hypertension patients?
Knowledge-focused CompletedThis study looked at 149 adults with high blood pressure and insomnia to understand how poor sleep might increase the risk of heart disease. Researchers used a type of talk therapy for insomnia (CBT-I) and measured changes in blood pressure and sleep quality over six months. The …
Phase: NA • Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 12, 2026 12:02 UTC