Children's Hospital Of Orange County

This study is testing whether repeated intravenous doses of an older drug called suramin (now called KZ101) can help improve social skills and other core symptoms in boys with autism. About 45 boys aged 5-14 will receive either the drug or a placebo for 8 weeks, then switch after…

This study is testing whether acupuncture can help reduce stomach pain in children with gut-brain interaction disorders, which cause chronic digestive issues. Researchers will compare real acupuncture to a fake 'sham' treatment in 96 kids aged 8-17 to see if it lowers pain intens…

This study is testing whether a small device placed on the outer ear can help reduce symptoms in children with post-concussion syndrome or long-lasting symptoms after COVID-19. The device uses gentle electrical stimulation and is worn for five days at a time. Researchers will mea…

This study aims to understand how heart and blood vessel problems develop in people with Mucopolysaccharidosis (MPS), a rare genetic disorder. Researchers will follow 240 participants (both with MPS and healthy matches) for four years, using yearly heart ultrasounds, blood tests,…