Children's Hospital Of Orange County

This study is testing whether peppermint oil capsules can improve symptoms of bladder and bowel dysfunction in children aged 8 to 17 who haven't gotten better with standard behavioral therapy. Thirty participants will take peppermint oil three times daily for 8 weeks, and researc…

This study follows 5 people with a rare, late-onset form of TPP1 deficiency (a brain disease) to track how their symptoms change over time. Researchers will use tests like brain scans, eye exams, and movement assessments to better understand the condition. The goal is to gather i…

This study follows 30 people with mucopolysaccharidoses (MPS) over three years to see how their heart and arteries change. Researchers use neck ultrasounds and blood tests to measure artery thickness, stiffness, and signs of inflammation. The goal is to better understand cardiova…