Could a Weight-Loss drug stop seizures in babies?
NCT ID NCT04289467
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests the drug fenfluramine in 10 children aged 12 to 36 months whose infantile spasms did not get better with standard treatments. The children take fenfluramine for 21 days, and doctors check brain waves and seizure diaries to see if the spasms stop. If it helps, they can continue treatment for up to 6 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- fenfluramine
- What this could lead to
- If it works, this could offer a new treatment option for children with hard-to-control infantile spasms.
- What could go wrong
- This is a very small, early-phase trial with only 10 children. It may not show clear benefit, and fenfluramine can have side effects like heart valve problems.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for INFANTILE SPASM are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Children's Hospital of Orange County
RECRUITINGOrange, California, 92868, United States
-
UCLA Health
NOT_YET_RECRUITINGLos Angeles, California, 90095, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.