Centre Hospitalier Universitaire Dijon

This study looks at the best way to stop tocilizumab in people with giant cell arteritis, a type of blood vessel inflammation. About 120 participants will either stop the drug suddenly or taper it slowly over time. The goal is to see which approach leads to fewer relapses and all…

This Phase 3 trial compares two drugs—methotrexate and tocilizumab—for treating giant cell arteritis, a condition that causes inflammation in large arteries. Both drugs are given alongside a tapering course of prednisone. The goal is to see if methotrexate, a cheaper and easier-t…

This Phase 3 trial tests whether a single high dose of the steroid methylprednisolone, given during surgery, can reduce major complications in 1200 people undergoing elective surgery for digestive cancers. The goal is to calm harmful inflammation that can worsen outcomes. Results…

This study compares vasopressin to the standard drug noradrenaline for managing blood pressure after heart surgery. The goal is to see if vasopressin reduces the number of patients who develop acute kidney failure or die. About 840 adults having scheduled heart surgery with a hea…