Centre Hospitalier Universitaire Dijon
Clinical trials sponsored by Centre Hospitalier Universitaire Dijon, explained in plain language.
-
Citrate or heparin: which keeps dialysis catheters working longer in the ICU?
Disease control CompletedThis study tested whether citrate or heparin is better at keeping dialysis catheters working without problems in ICU patients with sudden kidney failure. 405 adults were randomly assigned to receive one of the two locking solutions. The main goal was to see how long the first cat…
Phase: PHASE3 • Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Disease control
Last updated May 01, 2026 20:42 UTC
-
Heart surgery anesthesia showdown: which drug protects better?
Disease control CompletedThis study tested whether a specific inhaled anesthetic (sevoflurane) protects the heart better than an intravenous one (propofol) during planned aortic valve replacement surgery. The goal was to reduce heart muscle stress, measured by a protein called troponin. 82 adults having …
Phase: PHASE4 • Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Disease control
Last updated May 01, 2026 20:42 UTC
-
New CO2 method may better treat shock patients with high lactate
Disease control CompletedThis study tested a new way to treat high lactate levels in patients with shock. Doctors used a special CO2 measurement to decide which treatments (like fluids or medicines) to give. The goal was to see if this approach lowers lactate faster than usual care. 180 adults in intensi…
Phase: PHASE4 • Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Disease control
Last updated May 01, 2026 15:57 UTC
-
New scan may replace needle biopsy for artery disease diagnosis
Diagnosis CompletedThis study tested whether a PET/CT scan of the head arteries can accurately diagnose giant cell arteritis, a condition that causes inflamed blood vessels. Researchers compared the scan results to those from ultrasound and MRI in 70 patients over 50. The goal was to see if this no…
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Diagnosis
Last updated May 01, 2026 16:00 UTC
-
Could a body wrap help sepsis patients? new study explores
Symptom relief CompletedThis study tested whether a whole-body compression bandage could help reduce fluid buildup in ICU patients with severe sepsis or septic shock. 64 patients on mechanical ventilation received the bandage within 12 hours of admission. Researchers tracked daily fluid balance and chec…
Phase: NA • Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Symptom relief
Last updated May 01, 2026 20:42 UTC
-
New algorithm Fine-Tunes cochlear implants to boost hearing clarity
Symptom relief CompletedThis study tested a new method to adjust cochlear implant settings in 9 adults who have one implant and a hearing aid in the other ear. The goal was to improve how well they understand speech and perceive music by using an evolutionary algorithm to reassign sound frequencies. Res…
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Symptom relief
Last updated May 01, 2026 16:00 UTC
-
Hand acupuncture offers new hope for endometriosis pain
Symptom relief CompletedThis study tested whether Korean manupuncture, a type of hand acupuncture, can reduce pain in women with endometriosis. 74 women with endometriosis were randomly assigned to receive either real or placebo hand acupuncture. The goal was to see if this gentle, non-drug approach cou…
Phase: NA • Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Symptom relief
Last updated May 01, 2026 16:00 UTC
-
Brain zaps may curb smoking cravings in hardcore smokers
Symptom relief CompletedThis pilot study tested whether low-frequency repetitive transcranial magnetic stimulation (rTMS) to a specific brain area could reduce cravings in heavy smokers who had failed at least two previous quit attempts. 39 adults aged 18-65 who were highly dependent on nicotine and wan…
Phase: NA • Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Symptom relief
Last updated May 01, 2026 15:58 UTC
-
Massive database study reveals hidden child abuse numbers
Knowledge-focused CompletedThis study looked at hospital records of over 4 million children aged 0 to 5 in France to find out how often physical abuse happens and what leads to it. Researchers used national health databases to identify cases of abuse and compare them with other children. The goal is to bet…
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated May 01, 2026 20:42 UTC
-
Massive french study probes AntiTNFα risks in pregnant IBD patients
Knowledge-focused CompletedThis study looked at over 8,700 pregnant women with inflammatory bowel diseases (Crohn's or colitis) to see if using antiTNFα drugs during pregnancy is safe and follows guidelines. Researchers checked for complications in both mothers and babies up to one year after birth. The go…
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated May 01, 2026 20:42 UTC
-
New drain test may spot pancreatic leaks faster
Knowledge-focused CompletedThis study looked at 770 adults who had pancreatic surgery to see if measuring a different enzyme (lipase) in surgical drains could spot pancreatic leaks earlier than the usual test. The goal was to find a better way to catch these leaks before they cause serious problems like in…
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated May 01, 2026 20:42 UTC
-
New study tracks blood sugar in diabetic cancer patients during chemo
Knowledge-focused CompletedThis study looked at 103 diabetic adults starting chemotherapy for various cancers. Researchers used a Freestyle Libre continuous glucose monitor to track blood sugar levels around the clock. The goal was to see how often patients had dangerously low or high blood sugar, since ch…
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated May 01, 2026 20:42 UTC
-
Newer, faster heart valve surgery may cause rhythm issues
Knowledge-focused CompletedThis study looked at 198 patients who had a newer type of aortic valve replacement using a 'sutureless' valve that is faster to implant. The main goal was to check for heart rhythm problems after surgery. Researchers wanted to better understand these risks since few studies have …
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated May 01, 2026 20:42 UTC
-
Speedy gene test for fetuses shows promise in pilot study
Knowledge-focused CompletedThis study tested whether a fast version of genome sequencing (called exome sequencing) could help doctors find genetic causes for abnormalities seen on prenatal ultrasounds. Researchers enrolled 149 pregnant women whose fetuses had ultrasound findings suggesting a possible genet…
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated May 01, 2026 20:42 UTC
-
Scientists probe hidden fluid spaces to unravel septic shock mystery
Knowledge-focused CompletedThis study looked at the fluid between cells (interstitial fluid) in 26 intensive care patients with septic shock or non-septic shock. The goal was to understand how this fluid changes during severe infections, which could explain why swelling (edema) happens and worsens outcomes…
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated May 01, 2026 20:42 UTC
-
Scientists probe why obese women face more birth troubles
Knowledge-focused CompletedThis study looked at how obesity before pregnancy might affect the cells in the uterus that help with labor. Researchers used blood and tissue samples from 38 women having C-sections to see if inflammation and other factors change how these cells work. The goal is to better under…
Phase: NA • Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated May 01, 2026 16:00 UTC
-
Can virtual reality help amputees walk better? new study explores
Knowledge-focused CompletedThis study tested whether virtual reality (VR) is safe and tolerable for people with a leg amputation and for healthy volunteers during walking tasks. Researchers measured how many participants could complete walking in a VR environment without problems. The goal is to see if VR …
Phase: NA • Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated May 01, 2026 15:59 UTC
-
New study investigates cholesterol side effect of diabetes drug
Knowledge-focused CompletedThis study aims to understand why dapagliflozin, a diabetes medication, can increase bad cholesterol levels. Researchers will track how the body produces and removes cholesterol in 28 adults with type 2 diabetes over 6 months. Half will receive the drug, half a placebo. The resul…
Phase: PHASE4 • Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated May 01, 2026 15:59 UTC
-
Did mental health support help hospital staff during COVID? new study investigates.
Knowledge-focused CompletedThis study examined how hospital professionals handled stress during the COVID-19 pandemic and whether psychological and ethical support programs were helpful. Over 4,500 hospital workers took part. The goal was to understand what factors helped or hurt their mental health, not t…
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated May 01, 2026 15:58 UTC
-
Ultrasound could spot lung trouble before it starts in surgery patients
Knowledge-focused CompletedThis study tested whether a lung ultrasound done right after major abdominal surgery can help predict which patients will develop serious breathing problems. Researchers measured fluid in the lungs of 165 ICU patients and combined it with heart function tests. The goal was to fin…
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated May 01, 2026 15:57 UTC
-
New tool to hear what schizophrenia patients think about their teeth
Knowledge-focused CompletedThis study tested a questionnaire to understand how people with schizophrenia perceive their oral health. Researchers enrolled 59 patients to fill out surveys about their teeth and quality of life. The goal is to create a reliable tool to guide better dental prevention programs f…
Phase: NA • Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated May 01, 2026 15:57 UTC
-
Which embryo incubator works best? dijon study aims to find out
Knowledge-focused CompletedThis study compared two advanced embryo culture systems used in IVF with ICSI to see which one helps embryos implant better. 388 people took part. The goal was to find out if one system leads to more successful pregnancies by keeping embryos in a stable environment and allowing c…
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated May 01, 2026 15:57 UTC
-
Rare disease families share preferences on genetic testing surprises
Knowledge-focused CompletedThis study looked at how families of children with rare developmental disorders feel about receiving unexpected genetic findings from advanced DNA tests. Researchers surveyed and interviewed over 500 parents to understand their preferences and experiences. The goal is to improve …
Phase: NA • Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated May 01, 2026 15:57 UTC