Centre Hospitalier Universitaire De Nice

This study looks at whether empagliflozin, a diabetes medicine, can reduce protein leakage in urine for people with type 2 diabetes and very advanced chronic kidney disease (eGFR between 10 and 20). About 34 adults will take either empagliflozin or a placebo for 6 weeks each, and…

This study tests a daily pill called upadacitinib for people with severe forms of lichen planus, a chronic skin condition causing painful mouth sores or hair loss. About 56 adults will receive either the drug or a placebo for 16 weeks to see if it reduces symptoms. The goal is to…

This study tests whether adding hyperbaric oxygen (HBO) therapy to standard UVB light treatment can improve skin color in people with vitiligo. Five adults with non-segmental vitiligo will receive UVB twice a week for 24 weeks plus 40 HBO sessions over 8 weeks. The goal is to see…

This study tests whether methotrexate, a drug used for other types of arthritis, can slow joint damage in people with severe hand osteoarthritis that hasn't responded to usual treatments. About 170 participants will receive either methotrexate or a placebo for one year. The main …

This study tests whether a 4D virtual simulator called Modjaw® can help doctors better diagnose temporomandibular disorders (TMD), which cause jaw pain and affect nearly 1 in 3 adults. Researchers will compare the simulator's readings with MRI scans in 20 adults who have signs of…

This study tests a gentle, non-invasive ear stimulation device to help people over 70 improve swallowing after a stroke. Twenty participants will receive either the active device or a sham (inactive) device alongside standard speech therapy for three weeks. Researchers will measu…

This study tests a new approach to help older adults with dementia who feel apathetic (loss of interest and motivation). Ten participants in nursing homes will use virtual reality combined with personalized smells, sounds, and tastes to relive positive memories. The goal is to se…

This study watches 50 adults with generalized myasthenia gravis (gMG) who are taking the drug Rystiggo (rozanolixizumab). It does not test the drug itself, but instead uses a new patient questionnaire to track how symptoms like fatigue and muscle weakness change over 9 months. Th…

This study will see if using a robot for emergency abdominal surgery is possible and helpful. About 30 people needing urgent surgery for conditions like gallbladder problems or bowel blockages will be included. The goal is to see if robotic surgery can lower the chance of complic…

This study aims to understand how working night shifts in intensive care and emergency departments affects what and when healthcare workers eat. Researchers will compare their eating habits with those of night workers in other jobs. The goal is to find ways to improve health and …

This study looks at why some people with acute lymphoblastic leukemia (ALL) have severe allergic reactions to the chemotherapy drug asparaginase. Researchers will collect blood samples from 20 patients and test their immune cells in the lab to see if certain T cells become overac…

This study will describe how taking five or more medications (polypharmacy) affects healthy aging in people with HIV who are 75 or older. Researchers will collect data from 136 patients at Nice University Hospital to count their medications, identify common health problems, and c…

This study aims to create a faster, cheaper way to analyze mitochondrial DNA in muscle cells. Researchers will test a new digital PCR method on samples from 4 people with mitochondrial disease to see if it can reliably tell which genetic changes are harmful. If successful, this t…

This study looks at how two types of nerve diseases—hereditary and inflammatory—impact quality of life. Researchers will ask 60 adults with these conditions to fill out questionnaires about their daily functioning and well-being. The goal is to better understand patient needs and…