Cancer Trials Ireland
Clinical trials sponsored by Cancer Trials Ireland, explained in plain language.
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Breast cancer radiation showdown halted early
Disease control TerminatedThis study aimed to see if a precise type of external radiation (3D conformal) works as well as internal radiation (brachytherapy) for women with early-stage breast cancer after lumpectomy. Only 6 women took part before the trial was stopped. The goal was to control any remaining…
Phase: NA • Sponsor: Cancer Trials Ireland • Aim: Disease control
Last updated Apr 29, 2026 02:40 UTC
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Lung cancer trial aims to safely boost radiation to tumors
Disease control TerminatedThis study tested whether giving a higher dose of radiation directly to the main tumor, while keeping standard doses to surrounding areas, is safe for people with non-small cell lung cancer. Six participants received targeted radiation plus standard chemotherapy. The goal was to …
Phase: PHASE1, PHASE2 • Sponsor: Cancer Trials Ireland • Aim: Disease control
Last updated Apr 28, 2026 13:02 UTC
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New combo tackles tough pancreatic cancer resistance
Disease control TerminatedThis study tested whether combining two drugs, trametinib and hydroxychloroquine, could help overcome treatment resistance in people with advanced pancreatic cancer that had spread. It included 20 adults whose cancer had not responded to at least one prior therapy. The goal was t…
Phase: PHASE2 • Sponsor: Cancer Trials Ireland • Aim: Disease control
Last updated Apr 26, 2026 20:00 UTC
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Which radiation is gentler for rectal cancer?
Symptom relief TerminatedThis study compared two types of radiation therapy given before surgery for locally advanced rectal cancer. The goal was to see if one method caused fewer stomach and bowel side effects. About 94 people took part, but the study was stopped early.
Phase: PHASE1, PHASE2 • Sponsor: Cancer Trials Ireland • Aim: Symptom relief
Last updated Apr 28, 2026 13:02 UTC