New combo tackles tough pancreatic cancer resistance

NCT ID NCT05518110

First seen Apr 19, 2026 · Last updated Apr 24, 2026 · Updated 2 times

Summary

This study tested whether combining two drugs, trametinib and hydroxychloroquine, could help overcome treatment resistance in people with advanced pancreatic cancer that had spread. It included 20 adults whose cancer had not responded to at least one prior therapy. The goal was to see if the combination could slow or stop cancer growth, but the study was ended early.

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Contacts and locations

Locations

  • Mater Misericordiae University Hospital

    Dublin, D07 R2WY, Ireland

  • St Vincent's University Hospital

    Dublin, DO4 T6F4, Ireland

Conditions

Explore the condition pages connected to this study.