Cabaletta Bio

This study is testing a one-time cell therapy called CABA-201 for adults and children with rare autoimmune diseases that cause severe muscle weakness and inflammation. The goal is to see if this treatment can safely reduce disease activity and improve muscle strength, potentially…

This study is testing an experimental cell therapy called CABA-201 for adults with active lupus. Doctors will collect a patient's own immune cells, modify them to target the harmful cells causing lupus, and infuse them back. The main goals are to see if this one-time treatment is…

This study is testing two new cell therapies for adults with active pemphigus vulgaris, a painful autoimmune disease that causes severe blisters. Researchers are giving patients their own immune cells that have been specially engineered in a lab to target and potentially control …

This early-stage study is testing a single dose of an experimental cell therapy called CABA-201 for adults with active systemic sclerosis (scleroderma). The therapy, known as CAR T-cell therapy, is designed to target and remove a type of immune cell (B cells) thought to drive the…