Could CAR t cells tame scleroderma? new trial launches
NCT ID NCT06328777
First seen Sep 30, 2025 · Last updated Jun 11, 2026 · Updated 27 times
Summary
This early-stage study tests a new treatment called CABA-201 for people with systemic sclerosis (scleroderma), a disease that causes hardening of the skin and can damage organs. The treatment uses a patient's own immune cells, modified to target and destroy faulty B cells that drive the disease. The study will enroll 12 adults with active disease and significant organ involvement to check safety and how well the therapy works.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Columbia University Irving Medical Center
RECRUITINGNew York, New York, 10032, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Duke University
RECRUITINGDurham, North Carolina, 27710, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Mayo Clinic Florida
RECRUITINGJacksonville, Florida, 55905, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Mayo Clinic Rochester
RECRUITINGRochester, Minnesota, 55905, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Northwestern Memorial Hospital
RECRUITINGChicago, Illinois, 60611, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The University of Chicago Medical Center
RECRUITINGChicago, Illinois, 60637, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Kansas Medical Center
RECRUITINGKansas City, Kansas, 66160, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Michigan
RECRUITINGAnn Arbor, Michigan, 48109, United States
Contact Email: •••••@•••••
Contact Email: •••••@•••••
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University of Rochester
RECRUITINGRochester, New York, 14642, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Yale University
RECRUITINGNew Haven, Connecticut, 06519, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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