Beijing Gobroad Hospital

This early-phase trial tests a new treatment called FL-33 CAR T for people with acute myeloid leukemia that has come back or not responded to standard therapy. The treatment uses a patient's own immune cells, modified to find and attack leukemia cells. The study aims to find the …

This study tests a new treatment called CD19 CAR T cells for people with severe lupus that hasn't improved with standard therapies. The treatment uses a patient's own immune cells, modified in a lab to target and attack faulty immune cells driving the disease. The trial aims to s…

This early-stage trial is testing a new treatment called CT1190B CAR-T cell therapy for people with moderate to severe lupus or scleroderma that hasn't responded to standard treatments. The therapy uses a patient's own immune cells, modified to target and potentially calm the ove…

This study tests a new treatment using a patient's own immune cells, modified to target and attack faulty immune cells that cause autoimmune diseases. It is for people with severe, hard-to-treat conditions like lupus. The goal is to see if this therapy is safe and can control the…

This study tests two approaches for people with B-cell acute lymphoblastic leukemia that has come back or not responded to treatment. One group gets a sequence of two types of CAR T-cells (targeting CD19 and CD22), while the other gets one type of CAR T-cell followed by a stem ce…

This early study tests the safety of a new biologic drug called STR-P004 in 39 adults with autoimmune diseases that have not responded to standard treatments. Participants receive the drug by IV infusion, and researchers monitor for side effects and how the drug behaves in the bo…

This study tests a new treatment called CD5 CAR T-cells for people with T-cell cancers (like certain leukemias) that have returned or not responded to standard care. The treatment uses a patient's own immune cells or cells from a donor, which are modified in a lab to recognize an…

This early-phase study tests a new treatment called BiTE-EV for adults with relapsed or hard-to-treat B-cell leukemia. The main goals are to see if it is safe and if it can help control the disease. Only 3 participants will take the therapy every other day for 1-2 months and then…

This early-phase trial tests a two-step approach for people with B-cell acute lymphoblastic leukemia that has come back or not responded to treatment. First, patients receive donor-derived CD19 CAR T cells, then a stem cell transplant from the same donor, followed by donor-derive…

This study tests a new treatment using a patient's own immune cells, modified to target and attack harmful cells in three severe autoimmune diseases: lupus nephritis, systemic sclerosis, and Sjogren's syndrome with pulmonary hypertension. About 45 adults will receive a single inf…

This early-stage trial is testing a new treatment made from umbilical cord blood cells, called CD19-BCMA CAR-T cells, in 45 people with severe lupus, scleroderma, or Sjogren's syndrome with lung complications. The main goal is to check safety, especially serious side effects with…

This study tests whether adding cytokine-induced killer (CIK) cells can prevent CAR-T cells from wearing out too early in children and young adults with relapsed or hard-to-treat B-cell acute lymphoblastic leukemia. About 213 participants will be randomly assigned to receive eith…

This early-stage trial is testing a two-part treatment for advanced gastrointestinal cancer: a personalized mRNA vaccine (XH001) plus immune cells trained to attack the cancer. The study will enroll 18 adults whose cancer has not responded to standard treatments. The main goal is…

This early-phase trial tests a new treatment called TC-G203 for people with GPC3-positive solid tumors that have come back or spread after other treatments. The main goal is to find the safest dose and see if the therapy can shrink tumors. About 30 adults aged 18-75 who have not …

This study tests a new treatment called CD7 CAR T-cell therapy for people with T-cell cancers that have come back or not responded to standard treatments. The therapy uses a patient's own immune cells or cells from a donor, which are modified to find and attack cancer cells. The …

This early-stage study tests a new cell therapy that targets two proteins (BCMA and CD19) on myeloma cells. It is for patients whose multiple myeloma has returned or not responded to treatment and has spread outside the bone marrow. The main goal is to check the safety of this ap…

This early-phase trial is testing a new type of immune cell therapy that targets two proteins (BCMA and GPRC5D) on myeloma cells. It is for patients whose multiple myeloma has come back or stopped responding to treatment and has spread to other parts of the body. The main goal is…

This study tests a new type of CAR T-cell therapy that targets a protein called CD5 on cancer cells. It is for people with T-cell cancers that have come back or not responded to standard treatments. The therapy uses the patient's own immune cells or cells from a donor, which are …

This phase 1b trial is testing a personalized cell therapy called CT041 CAR-T for people with advanced stomach or gastroesophageal junction cancer. After completing standard first-line treatment, 20 participants will receive up to three infusions of their own engineered immune ce…

This early-stage trial is testing a new treatment called OL-CD19-GDT, which uses specially engineered immune cells (CAR-T cells) from a healthy donor to target and destroy faulty immune cells in people with severe autoimmune diseases like systemic sclerosis and Sjogren's syndrome…