Engineered immune cells take on stomach cancer in new trial

NCT ID NCT07179484

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 1b trial is testing a personalized cell therapy called CT041 CAR-T for people with advanced stomach or gastroesophageal junction cancer. After completing standard first-line treatment, 20 participants will receive up to three infusions of their own engineered immune cells. The goal is to see if this approach can delay cancer progression and improve survival, while monitoring safety and how the cells behave in the body.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

CT041 autologous CAR-T cell injection

What this could lead to

If successful, this could offer a new treatment option to control advanced gastric cancer after initial therapy, potentially extending time without disease progression.

What could go wrong

This is a small, early-phase trial (20 participants) focused on safety and dosing, so results may not confirm effectiveness. CAR-T therapy carries risks like cytokine release syndrome and neurological side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

gastroesophageal junction adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • BeijingGoBroadH

    RECRUITING

    Beijing, 100142, China

    Contact