Can immune booster cells revive failing CAR-T therapy in leukemia?

NCT ID NCT06389305

First seen Feb 26, 2026 · Last updated Jun 11, 2026 · Updated 16 times

Summary

This study tests whether adding cytokine-induced killer (CIK) cells can prevent CAR-T cells from wearing out too early in children and young adults with relapsed or hard-to-treat B-cell acute lymphoblastic leukemia. About 213 participants will be randomly assigned to receive either control cells, CIK cells, or enhanced mRNA-CIK cells. The main goal is to see if CIK therapy improves how long patients stay free of relapse or treatment failure.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing GoBroad Hospital

    RECRUITING

    Beijing, Beijing Municipality, 102206, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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