Bayer

This study tested a new drug called larotrectinib in 75 adults with advanced solid tumors that have a specific gene change (NTRK fusion). The main goal was to check the drug's safety and find the right dose. Participants had cancers that stopped responding to other treatments or …

This study tested a new drug called BAY 3283142 in 1222 adults with chronic kidney disease and high protein levels in their urine. The drug works by relaxing blood vessels and was added to standard treatments. Researchers measured changes in urine protein after 16 weeks to see if…

This study looked at two drugs, darolutamide and enzalutamide, in men with prostate cancer that had come back after initial treatment but had not yet been treated with hormone therapy. The goal was to see how each drug affects testosterone levels and side effects like breast tend…

This study tested a new scoring method to help doctors choose the best Jivi treatment plan for people with hemophilia A. 21 participants switched from standard factor VIII products to Jivi, and their dose frequency was tailored based on their risk of bleeding. The goal was to see…

This early-phase study tested a new drug called BAY 2862789 in 45 people with advanced solid tumors, including a type of lung cancer. The drug works by activating the body's immune T-cells to fight cancer. The main goals were to check safety, find the best dose, and see how the d…

This study checked the safety of aflibercept eye injections in 100 Indian adults with diabetic macular edema (DME), a diabetes complication that causes vision loss. Participants received injections every 4 weeks for 5 months, then every 8 weeks for a total of 48 weeks. The main g…

This study tested whether the drug finerenone can slow the worsening of chronic kidney disease in people who do not have diabetes. About 1,580 adults took either finerenone or a placebo pill daily, along with their usual kidney medications, for up to 50 months. Researchers measur…

This study tested the safety of a new drug, BAY3283142, in 75 adults with mild to moderate high blood pressure. The drug helps relax blood vessels and is being developed for chronic kidney disease. Participants took different doses or a placebo over several weeks, with researcher…

This study looked at how well the drug vericiguat works for Chinese adults with chronic heart failure (a condition where the heart doesn't pump blood well). Researchers compared 2400 patients taking vericiguat to similar patients receiving standard care. The goal was to see if ve…

This study looked at how much of the drug aflibercept gets into the blood when a high dose (8 mg) is injected into both eyes of people with diabetic macular edema or wet age-related macular degeneration. Fifty-one adults received the injections and had blood samples taken to meas…

This study tested a new medicine called elinzanetant to see if it can reduce hot flashes in women after menopause. About 400 women took either the drug or a placebo daily for up to 26 weeks. The researchers tracked how often and how severe the hot flashes were using an electronic…

This study looked at how moderate liver problems affect the way the body handles a new cancer medicine called sevabertinib. About 20 people (10 with liver impairment and 10 healthy) took a single dose and had their blood levels measured. The goal is to help doctors decide the rig…

This study looked at how well Kovaltry works and how safe it is for people with hemophilia A when used in everyday medical practice. Researchers followed 230 patients who were already prescribed Kovaltry and recorded any side effects and how well the drug controlled bleeding epis…

This study looked at the long-term safety of Radium-223 in 1,472 men with metastatic castration-resistant prostate cancer. Researchers tracked side effects, bone marrow problems, and the risk of developing new cancers after treatment. The goal was to understand the drug's safety …

This study looked at nearly 5,000 Japanese adults with chronic heart failure who started taking the drug vericiguat as part of their regular care. Researchers used hospital records to track outcomes like death, heart-related hospital stays, and how long patients stayed on the med…

This study looked at how the drug radium-223 moves through bones in men with prostate cancer that has spread to the bones. Researchers wanted to see how much of the drug goes to healthy bone versus tumor areas. The study involved 46 men who received up to 6 injections of radium-2…

This study looked at the safety of the blood thinner rivaroxaban in 1500 Japanese people with peripheral artery disease (PAD) who had surgery to improve blood flow to their legs. Researchers used existing health records to track bleeding events and heart-related deaths. No new tr…

This study looked at medical records from over 5,700 adults in Japan who had sepsis (blood poisoning) to learn how many also developed a serious clotting condition called DIC. Researchers collected information from hospital databases to track DIC rates and the scoring tools docto…

This study looked at how well new pill forms of elinzanetant are absorbed by the body compared to the original soft gel capsule. Eighteen healthy women aged 18-65 took single and multiple doses of different pill versions. Researchers measured drug levels in the blood and checked …