High-Dose eye drug tested in both eyes for common vision disorders

NCT ID NCT06591598

First seen Oct 31, 2025 · Last updated May 15, 2026 · Updated 29 times

Summary

This study looked at how much of the drug aflibercept gets into the blood when a high dose (8 mg) is injected into both eyes of people with diabetic macular edema or wet age-related macular degeneration. Fifty-one adults received the injections and had blood samples taken to measure drug levels. The goal was to gather safety and drug-exposure information, not to test if the treatment works.

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Contacts and locations

Locations

  • Axon Clinical, s.r.o.

    Prague, 150 00, Czechia

  • Budapest Retina Associates

    Budapest, 1133, Hungary

  • Debreceni Egyetem Klinikai Kozpont

    Debrecen, 4032, Hungary

  • Fakultna nemocnica s poliklinikou Zilina

    Žilina, 012 07, Slovakia

  • Fakultní nemocnice Královské Vinohrady - Urologická klinikay

    Prague, 10034, Czechia

  • Univerzitna nemocnica Bratislava, Nem. Sv. Cyrila a Metoda

    Bratislava, 851 07, Slovakia

Conditions

Explore the condition pages connected to this study.