Liver health may change how cancer drug works

NCT ID NCT07102095

First seen Feb 14, 2026 · Last updated May 15, 2026 · Updated 7 times

Summary

This study looked at how moderate liver problems affect the way the body handles a new cancer medicine called sevabertinib. About 20 people (10 with liver impairment and 10 healthy) took a single dose and had their blood levels measured. The goal is to help doctors decide the right dose for cancer patients who also have liver disease.

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Contacts and locations

Locations

  • Clinical Pharmacology of Miami - Oncology

    Miami, Florida, 33014, United States

  • Orlando Clinical Research Center

    Orlando, Florida, 32809, United States

Conditions

Explore the condition pages connected to this study.